Product Description:
High-quality, safe clearance
Contact Ada, you would never regret.
YK11 CAS:431579-34-9
Category:Sarms, Prohormones
Properties:White Powder
Grade:Pharmaceutical Grade
Â
What is YK11?
1. (17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel androgen receptor (AR) partial agonist. as well as by dihydrotestosterone (DHT).
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Â
2.Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties ofYK11.
 How YK11 Works?
3.YK11 attaches itself to the AR (androgen receptor), but only inducts methods that lead to the traditional side effects of androgens such as growth of body hair and prostate and enhanced aggression - to a restricted degree.
Most SARMS have quite limited androgenic side effects, but frequently only quite few anabolic effects when likened to testosterone. But, this doesn't occur for YK11 as reported in Biological and Pharmaceutical Bulletin in 2013.
Â
4.YK11 induces muscle cells to make more follistatin (more than DHT does) -Â a strong myostatin inhibitor. YK11 works through the androgen receptor.
With that said, YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.
Â
Conclusion:
1.YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it's as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.
2.SRM YK-11 is a powerful SARM supplement promoting massive lean muscle gains which is a great benefit for those wanting to have an aesthetic and shredded physique.
Dosages and Suggestion:
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.
Place of origin:China
Certificate:ISO9001, KOSHER, SGS
Minimum order quantity :Â 5 Grams
Production capacity :Â 1000 Kilograms/Month
Packing :Foil bag/tin or as your request
Payment :T/T, Western Union, MoneyGram
Port :Â Shanghai,Shenzhen, Hongkong
Shipment method :EMS, DHL, FeDex, UPS, etc
Delivery time:Safe &Â timely, around 8Â days after payment.
1.Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years.
2.Great quality, purity and favourable.
Our company is a professional leading factory in China in pharmaceutical area.Good quality is one of our secret success.
3.Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
4.Package:
Professional packing with professional materials
5.Competitive Prices :Â Low price with high qulity
6.Good after-sales service:Â
making all efforts to meet customers' need.
Our products(raw material),everything you expect to find.
Â
Local anesthetics:Proparacaine hydrochloride, Levobupivacaine hydrochloride , Bupivacaine hydrochloride and so on.
Polypeptide:GHRP-2,GHRP-6 ,T3, T4, CJC-1295 and so on.
Weight loss medicine :Lorcaserin ,Orlistat, Synephrine and so on.Â
Pharmaceutical Intermediates:Anti-cancer,Anti-virus,Anti-inflammatory and so on.Â
SARMS :YK11 , RAD-140 , LGD4033, MK-677 and so on.
GW-501516/Cardarine
MK-2866/Ostarine
LGD-4033/Ligandrol
SR9009
MK-677/Nutrobal
RAD-140
YK-11
AICAR/Acadesine
GTX007/Andarine
SR9011Â
| Adrafin | to increases the brain neurotransmitter, hypocretin |
| Aniracetam | to improve learning and memory, increase perception, reduce anxiety and increase reflexes |
| Carpedon | anti-amnesic, antidepressant,anticonvulsant, antipsychotic, anxiolytic, andmemory enhancement effects |
| Centrophenoxine | shown to improve memory, have a mentally stimulating effect, and improve general cognition for elder patients |
| Coluracetam | potential use in prevention and treatment of ischemicretinopathy and retinaland optic nerve injury and a potential therapeutic drug for schizophrenia |
| IDRA-21 | shown to be valuable in memory improvement, cognitive enhancement, stimulation, and reversing cognitive deficits |
| Modafin | to improve ability to focus in duration and intensity, analytic capabilities, memory recall and rententio, mood and well-being. |
| Noopept | to offer many benefits in terms of improving memory, learning capacity, focus, and concentration |
| NSI-189 | to stimulate neurogenesis of human hippocampal stem cells in vitro and in vivo |
| Oxiracetam | highly effective at increasing attention span, memory, mental energy and cognitive  processing |
| PRL-8-53 | to improve learning and memory |
| Sunifiram | as an ampakine because it gains its effectiveness through the increasing glycine receptor binding |
| Unifiram | to improve learning and memory, increase perception, reduce anxiety and increase reflexes |
| Vinpocetine | shown to be valuable in protecting heart, visual, and hearing functions, among other benefits |
Related products:
Â
Â
Â
Â
Â
Â
Â
Epiandrosteron (CAS: 481-29-8)
DHE. A(Dehydroepiandrosteron) (CAS: 53-43-0)
Tadalafi(Ciali) (CAS: 171596-29-5)
Vardenafil (Levitr) (CAS: 224785-91-5)
Weight Loss Powder:
Sibutramin Hydrochloride
Phentermin Hydrochloride(CAS: 1197-21-3)
L(-)-Carnitine (CAS: 541-15-1)
Rimonabant (CAS: 158681-13-1)
Antineoplastic Powder:
Anastrozol (Arimidex) (CAS: 120511-73-1)
L-Triiodothyronine(T3) (CAS: 55-06-1)
Trilostan (CAS: 13647-35-3)
Formestan (CAS: 566-48-3)
Estrogen Hormone/Estrogen-blocking Powder:
Â
Â
Progesterone (CAS: 57-83-0)
Estradiol (CAS: 50-28-2)
Estradiol valerate (CAS: 979-32-8)
Diethylstilbestrol (CAS: 56-53-1)
Hexestrol (CAS: 84-16-2)
Surface Anesthesia Powder:
Â
Â
Â
Â
Product Description:
High-quality, safe clearance
Contact Ada, you would never regret.
YK11 CAS:431579-34-9
Category:Sarms, Prohormones
Properties:White Powder
Grade:Pharmaceutical Grade
Â
What is YK11?
1. (17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel androgen receptor (AR) partial agonist. as well as by dihydrotestosterone (DHT).
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Â
2.Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties ofYK11.
 How YK11 Works?
3.YK11 attaches itself to the AR (androgen receptor), but only inducts methods that lead to the traditional side effects of androgens such as growth of body hair and prostate and enhanced aggression - to a restricted degree.
Most SARMS have quite limited androgenic side effects, but frequently only quite few anabolic effects when likened to testosterone. But, this doesn't occur for YK11 as reported in Biological and Pharmaceutical Bulletin in 2013.
Â
4.YK11 induces muscle cells to make more follistatin (more than DHT does) -Â a strong myostatin inhibitor. YK11 works through the androgen receptor.
With that said, YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.
Â
Conclusion:
1.YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it's as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.
2.SRM YK-11 is a powerful SARM supplement promoting massive lean muscle gains which is a great benefit for those wanting to have an aesthetic and shredded physique.
Dosages and Suggestion:
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.
Place of origin:China
Certificate:ISO9001, KOSHER, SGS
Minimum order quantity :Â 5 Grams
Production capacity :Â 1000 Kilograms/Month
Packing :Foil bag/tin or as your request
Payment :T/T, Western Union, MoneyGram
Port :Â Shanghai,Shenzhen, Hongkong
Shipment method :EMS, DHL, FeDex, UPS, etc
Delivery time:Safe &Â timely, around 8Â days after payment.
1.Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years.
2.Great quality, purity and favourable.
Our company is a professional leading factory in China in pharmaceutical area.Good quality is one of our secret success.
3.Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
4.Package:
Professional packing with professional materials
5.Competitive Prices :Â Low price with high qulity
6.Good after-sales service:Â
making all efforts to meet customers' need.
Our products(raw material),everything you expect to find.
Â
Local anesthetics:Proparacaine hydrochloride, Levobupivacaine hydrochloride , Bupivacaine hydrochloride and so on.
Polypeptide:GHRP-2,GHRP-6 ,T3, T4, CJC-1295 and so on.
Weight loss medicine :Lorcaserin ,Orlistat, Synephrine and so on.Â
Pharmaceutical Intermediates:Anti-cancer,Anti-virus,Anti-inflammatory and so on.Â
SARMS :YK11 , RAD-140 , LGD4033, MK-677 and so on.
GW-501516/Cardarine
MK-2866/Ostarine
LGD-4033/Ligandrol
SR9009
MK-677/Nutrobal
RAD-140
YK-11
AICAR/Acadesine
GTX007/Andarine
SR9011Â
| Adrafin | to increases the brain neurotransmitter, hypocretin |
| Aniracetam | to improve learning and memory, increase perception, reduce anxiety and increase reflexes |
| Carpedon | anti-amnesic, antidepressant,anticonvulsant, antipsychotic, anxiolytic, andmemory enhancement effects |
| Centrophenoxine | shown to improve memory, have a mentally stimulating effect, and improve general cognition for elder patients |
| Coluracetam | potential use in prevention and treatment of ischemicretinopathy and retinaland optic nerve injury and a potential therapeutic drug for schizophrenia |
| IDRA-21 | shown to be valuable in memory improvement, cognitive enhancement, stimulation, and reversing cognitive deficits |
| Modafin | to improve ability to focus in duration and intensity, analytic capabilities, memory recall and rententio, mood and well-being. |
| Noopept | to offer many benefits in terms of improving memory, learning capacity, focus, and concentration |
| NSI-189 | to stimulate neurogenesis of human hippocampal stem cells in vitro and in vivo |
| Oxiracetam | highly effective at increasing attention span, memory, mental energy and cognitive  processing |
| PRL-8-53 | to improve learning and memory |
| Sunifiram | as an ampakine because it gains its effectiveness through the increasing glycine receptor binding |
| Unifiram | to improve learning and memory, increase perception, reduce anxiety and increase reflexes |
| Vinpocetine | shown to be valuable in protecting heart, visual, and hearing functions, among other benefits |
Related products:
Â
Â
Â
Â
Â
Â
Â
Epiandrosteron (CAS: 481-29-8)
DHE. A(Dehydroepiandrosteron) (CAS: 53-43-0)
Tadalafi(Ciali) (CAS: 171596-29-5)
Vardenafil (Levitr) (CAS: 224785-91-5)
Weight Loss Powder:
Sibutramin Hydrochloride
Phentermin Hydrochloride(CAS: 1197-21-3)
L(-)-Carnitine (CAS: 541-15-1)
Rimonabant (CAS: 158681-13-1)
Antineoplastic Powder:
Anastrozol (Arimidex) (CAS: 120511-73-1)
L-Triiodothyronine(T3) (CAS: 55-06-1)
Trilostan (CAS: 13647-35-3)
Formestan (CAS: 566-48-3)
Estrogen Hormone/Estrogen-blocking Powder:
Â
Â
Progesterone (CAS: 57-83-0)
Estradiol (CAS: 50-28-2)
Estradiol valerate (CAS: 979-32-8)
Diethylstilbestrol (CAS: 56-53-1)
Hexestrol (CAS: 84-16-2)
Surface Anesthesia Powder:
Â
Â
Â
Â
Hex Bolt
Hex Bolt
Hebei Qianmu Fastener Manufacturing Co., Ltd , https://www.qmjgjfasteners.com